Golgi SNAP receptor complex member 2 (GOSR2)

About Golgi SNAP receptor complex member 2

Golgi SNAP receptor complex member 2 (GOSR2) is a protein from Homo sapiens identified by UniProt accession O14653, 212 residues long. MolForge cross-references it against 0 known binders and 103 disease associations.

Target properties

Protein name	Golgi SNAP receptor complex member 2
UniProt accession	O14653
Gene	GOSR2
Organism	Homo sapiens
Length	212 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (103)

Diseases linked to this target (Open Targets).

progressive myoclonic epilepsy type 6 · score 0.76
muscular dystrophy, congenital, with or without seizures · score 0.64
Progressive myoclonic epilepsy · score 0.55
neurodegenerative disease · score 0.53
genetic disorder · score 0.48
progressive myoclonus epilepsy · score 0.38
systolic blood pressure · score 0.36
electrocardiography · score 0.33
pulse pressure measurement · score 0.32
blood urea nitrogen measurement · score 0.31

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O14653-F1	alphafold	PREDICTED	83.12	—

Amino-acid sequence (212 residues)

MDPLFQQTHK QVHEIQSCMG RLETADKQSV HIVENEIQAS IDQIFSRLER LEILSSKEPP NKRQNARLRV DQLKYDVQHL QTALRNFQHR RHAREQQERQ REELLSRTFT TNDSDTTIPM DESLQFNSSL QKVHNGMDDL ILDGHNILDG LRTQRLTLKG TQKKILDIAN MLGLSNTVMR LIEKRAFQDK YFMIGGMLLT CVVMFLVVQY LT

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards