Tumor protein p53-inducible protein 11 (TP53I11)

About Tumor protein p53-inducible protein 11

Tumor protein p53-inducible protein 11 (TP53I11) is a protein from Homo sapiens identified by UniProt accession O14683, 189 residues long. MolForge cross-references it against 0 known binders and 45 disease associations.

Target properties

Protein name	Tumor protein p53-inducible protein 11
UniProt accession	O14683
Gene	TP53I11
Organism	Homo sapiens
Length	189 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (45)

Diseases linked to this target (Open Targets).

neurofibrillary tangles measurement · score 0.30
resting heart rate · score 0.29
diet measurement · score 0.28
gonorrhea · score 0.08
intraocular pressure measurement · score 0.08
cancer · score 0.08
vital capacity · score 0.07
brain measurement · score 0.07
schizophrenia · score 0.06
reaction time measurement · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O14683-F1	alphafold	PREDICTED	75.58	—

Amino-acid sequence (189 residues)

MAAKQPPPLM KKHSQTDLVS RLKTRKILGV GGEDDDGEVH RSKISQVLGN EIKFTIREPL GLRVWQFVSA VLFSGIAIMA LAFPDQLYDA VFDGAQVTSK TPIRLYGGAL LSISLIMWNA LYTAEKVIIR WTLLTEACYF GVQFLVVTAT LAETGLMSLG ILLLLVSRLL FVVISIYYYY QVGRRPKKA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards