About Zinc finger protein 197
Zinc finger protein 197 (ZNF197) is a protein
from Homo sapiens identified by UniProt accession
O14709, 1029 residues long.
MolForge cross-references it against 0 known binders and
12 disease associations.
Target properties
| Protein name | Zinc finger protein 197 |
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| UniProt accession | O14709 |
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| Gene | ZNF197 |
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| Organism | Homo sapiens |
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| Length | 1029 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (12)
Diseases linked to this target (Open Targets).
- particulate matter air pollution measurement · score 0.08
- depressive symptom measurement · score 0.08
- urate measurement · score 0.08
- unipolar depression · score 0.07
- cystatin C measurement · score 0.06
- major depressive disorder · score 0.06
- C-reactive protein measurement · score 0.03
- Sepsis · score 0.01
- glioblastoma multiforme · score 0.01
- neoplasm · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O14709-F1 | alphafold | PREDICTED | 68.85 | — |
Amino-acid sequence (1029 residues)
MTRENVAHNA LRQEGLVKGK DDTWKWGTSF QGSSSSVWET SHLHFRQLRY HETSGPQEAL SRLRELCRRW LRPEARTKAQ ILELLVLEQF LSILPGEIRT WVQLHHPGSG EEAVALVEEL QKDLDGPAIQ VPVLVKDQDT LQKVVSAPGT TLPPVLPGSH IAAEICPHPP TDLVAFNLQD PQHDSPAPEA SALSQEENPR NQLMALMLLT AQPQELVMFE EVSVCFTSEE WACLGPIQRA LYWDVMLENY GNVTSLEWET MTENEEVTSK PSSSQRADSH KGTSKRLQGS VPQVLDFEEE CEWQVLASQW GNETDERADT VKKVSLCERD KKKRTPPEKQ GQKWKELGDS LTFGSAISES LIGTEGKKFY KCDMCCKHFN KISHLINHRR IHTGEKPHKC KECGKGFIQR SSLLMHLRNH SGEKPYKCNE CGKAFSQSAY LLNHQRIHTG EKPYKCKECG KGFYRHSGLI IHLRRHSGER PYKCNECGKV FSQNAYLIDH QRLHKGEEPY KCNKCQKAFI LKKSLILHQR IHSGEKPYKC DECGKTFAQT TYLIDHQRLH SAENPYKCKE CGKVFIRSKS LLLHQRVHTE KKTFGCKKCG KIFSSKSNFI DHKRMHSREK PYKCTECGKA FTQSAYLFDH QRLHNGEKPY ECNECGKVFI LKKSLILHQR FHTGENLYEC KDCGKVFGSN RNLIDHERLH NGEKPYECRE CGKTFIMSKS FMVHQKLHTQ EKAYKCEDCG KAFSYNSSLL VHRRIHTGEK PFECSECGRA FSSNRNLIEH KRIHSGEKPY ECDECGKCFI LKKSLIGHQR IHTREKSYKC NDCGKVFSYR SNLIAHQRIH TGEKPYACSE CGKGFTYNRN LIEHQRIHSG EKTYECHVCR KVLTSSRNLM VHQRIHTGEK PYKCNECGKD FSQNKNLVVH QRMHTGEKPY ECDKCRKSFT SKRNLVGHQR IHTGEKPYGC NDCSKVFRQR KNLTVHQKIH TDEKPCECDV SEKEFSQTSN LHLQQKIHTI EEFSWLQNTN ESKIEIQKI
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