Visual pigment-like receptor peropsin (RRH)

About Visual pigment-like receptor peropsin

Visual pigment-like receptor peropsin (RRH) is a protein from Homo sapiens identified by UniProt accession O14718, 337 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.

Target properties

Protein name	Visual pigment-like receptor peropsin
UniProt accession	O14718
Gene	RRH
Organism	Homo sapiens
Length	337 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (28)

Diseases linked to this target (Open Targets).

Stargardt disease · score 0.33
lean body mass · score 0.33
DNA methylation · score 0.30
body weight · score 0.29
fat body mass · score 0.24
ovarian cancer · score 0.23
whole body water mass · score 0.21
body height · score 0.17
congenital stationary night blindness · score 0.16
base metabolic rate measurement · score 0.14

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O14718-F1	alphafold	PREDICTED	85.74	—

Amino-acid sequence (337 residues)

MLRNNLGNSS DSKNEDGSVF SQTEHNIVAT YLIMAGMISI ISNIIVLGIF IKYKELRTPT NAIIINLAVT DIGVSSIGYP MSAASDLYGS WKFGYAGCQV YAGLNIFFGM ASIGLLTVVA VDRYLTICLP DVGRRMTTNT YIGLILGAWI NGLFWALMPI IGWASYAPDP TGATCTINWR KNDRSFVSYT MTVIAINFIV PLTVMFYCYY HVTLSIKHHT TSDCTESLNR DWSDQIDVTK MSVIMICMFL VAWSPYSIVC LWASFGDPKK IPPPMAIIAP LFAKSSTFYN PCIYVVANKK FRRAMLAMFK CQTHQTMPVT SILPMDVSQN PLASGRI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards