About CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (CDIPT) is a protein
from Homo sapiens identified by UniProt accession
O14735, 213 residues long.
MolForge cross-references it against 0 known binders and
54 disease associations.
Target properties
| Protein name | CDP-diacylglycerol--inositol 3-phosphatidyltransferase |
|---|
| UniProt accession | O14735 |
|---|
| Gene | CDIPT |
|---|
| Organism | Homo sapiens |
|---|
| Length | 213 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (54)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.22
- colorectal carcinoma · score 0.15
- genetic disorder · score 0.12
- oral squamous cell carcinoma · score 0.07
- body fat distribution · score 0.02
- alcohol consumption measurement · score 0.02
- neoplasm · score 0.02
- chronic obstructive pulmonary disease · score 0.01
- leukoplakia · score 0.01
- Cataract · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O14735-F1 | alphafold | PREDICTED | 89.98 | — |
Amino-acid sequence (213 residues)
MPDENIFLFV PNLIGYARIV FAIISFYFMP CCPLTASSFY LLSGLLDAFD GHAARALNQG TRFGAMLDML TDRCSTMCLL VNLALLYPGA TLFFQISMSL DVASHWLHLH SSVVRGSESH KMIDLSGNPV LRIYYTSRPA LFTLCAGNEL FYCLLYLFHF SEGPLVGSVG LFRMGLWVTA PIALLKSLIS VIHLITAARN MAALDAADRA KKK
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