Programmed cell death protein 5 (PDCD5)

About Programmed cell death protein 5

Programmed cell death protein 5 (PDCD5) is a protein from Homo sapiens identified by UniProt accession O14737, 125 residues long. MolForge cross-references it against 0 known binders and 146 disease associations.

Target properties

Protein name	Programmed cell death protein 5
UniProt accession	O14737
Gene	PDCD5
Organism	Homo sapiens
Length	125 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (146)

Diseases linked to this target (Open Targets).

Red cell distribution width · score 0.48
mean corpuscular volume · score 0.48
mean corpuscular hemoglobin concentration · score 0.47
platelet count · score 0.46
mean platelet volume · score 0.45
mean corpuscular hemoglobin · score 0.45
neurodegenerative disease · score 0.44
HbA1c measurement · score 0.43
blood protein measurement · score 0.40
Immature Reticulocyte Fraction Measurement · score 0.38

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O14737-F1	alphafold	PREDICTED	75.12	—

Amino-acid sequence (125 residues)

MADEELEALR RQRLAELQAK HGDPGDAAQQ EAKHREAEMR NSILAQVLDQ SARARLSNLA LVKPEKTKAV ENYLIQMARY GQLSEKVSEQ GLIEILKKVS QQTEKTTTVK FNRRKVMDSD EDDDY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards