About Trace amine-associated receptor 5
Trace amine-associated receptor 5 (TAAR5) is a protein
from Homo sapiens identified by UniProt accession
O14804, 337 residues long.
MolForge cross-references it against 0 known binders and
34 disease associations.
Target properties
| Protein name | Trace amine-associated receptor 5 |
|---|
| UniProt accession | O14804 |
|---|
| Gene | TAAR5 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 337 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (34)
Diseases linked to this target (Open Targets).
- glioblastoma multiforme · score 0.24
- lung adenocarcinoma · score 0.18
- cutaneous melanoma · score 0.17
- endometrial cancer · score 0.16
- thyroid gland adenocarcinoma · score 0.16
- medulloblastoma · score 0.13
- low grade glioma · score 0.12
- squamous cell lung carcinoma · score 0.12
- breast adenocarcinoma · score 0.10
- prostate adenocarcinoma · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O14804-F1 | alphafold | PREDICTED | 85.18 | — |
Amino-acid sequence (337 residues)
MRAVFIQGAE EHPAAFCYQV NGSCPRTVHT LGIQLVIYLA CAAGMLIIVL GNVFVAFAVS YFKALHTPTN FLLLSLALAD MFLGLLVLPL STIRSVESCW FFGDFLCRLH TYLDTLFCLT SIFHLCFISI DRHCAICDPL LYPSKFTVRV ALRYILAGWG VPAAYTSLFL YTDVVETRLS QWLEEMPCVG SCQLLLNKFW GWLNFPLFFV PCLIMISLYV KIFVVATRQA QQITTLSKSL AGAAKHERKA AKTLGIAVGI YLLCWLPFTI DTMVDSLLHF ITPPLVFDIF IWFAYFNSAC NPIIYVFSYQ WFRKALKLTL SQKVFSPQTR TVDLYQE
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