About Secretory carrier-associated membrane protein 3
Secretory carrier-associated membrane protein 3 (SCAMP3) is a protein
from Homo sapiens identified by UniProt accession
O14828, 347 residues long.
MolForge cross-references it against 0 known binders and
43 disease associations.
Target properties
| Protein name | Secretory carrier-associated membrane protein 3 |
|---|
| UniProt accession | O14828 |
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| Gene | SCAMP3 |
|---|
| Organism | Homo sapiens |
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| Length | 347 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (43)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.19
- Crohn's disease · score 0.18
- risk-taking behaviour · score 0.14
- type 2 diabetes mellitus · score 0.13
- hepatocellular carcinoma · score 0.10
- neoplasm · score 0.10
- HbA1c measurement · score 0.08
- blood protein measurement · score 0.08
- triple-negative breast cancer · score 0.07
- vitamin D measurement · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O14828-F1 | alphafold | PREDICTED | 76.60 | — |
Amino-acid sequence (347 residues)
MAQSRDGGNP FAEPSELDNP FQDPAVIQHR PSRQYATLDV YNPFETREPP PAYEPPAPAP LPPPSAPSLQ PSRKLSPTEP KNYGSYSTQA SAAAATAELL KKQEELNRKA EELDRREREL QHAALGGTAT RQNNWPPLPS FCPVQPCFFQ DISMEIPQEF QKTVSTMYYL WMCSTLALLL NFLACLASFC VETNNGAGFG LSILWVLLFT PCSFVCWYRP MYKAFRSDSS FNFFVFFFIF FVQDVLFVLQ AIGIPGWGFS GWISALVVPK GNTAVSVLML LVALLFTGIA VLGIVMLKRI HSLYRRTGAS FQKAQQEFAA GVFSNPAVRT AAANAAAGAA ENAFRAP
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