About Transcription regulator protein BACH1
Transcription regulator protein BACH1 (BACH1) is a protein
from Homo sapiens identified by UniProt accession
O14867, 736 residues long.
MolForge cross-references it against 0 known binders and
50 disease associations.
Target properties
| Protein name | Transcription regulator protein BACH1 |
|---|
| UniProt accession | O14867 |
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| Gene | BACH1 |
|---|
| Organism | Homo sapiens |
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| Length | 736 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (50)
Diseases linked to this target (Open Targets).
- aspartate aminotransferase measurement · score 0.36
- Red cell distribution width · score 0.35
- hemoglobin measurement · score 0.35
- high density lipoprotein cholesterol measurement · score 0.32
- electrocardiography · score 0.28
- mean corpuscular hemoglobin concentration · score 0.27
- creatine kinase measurement · score 0.26
- pancreatic carcinoma · score 0.26
- apolipoprotein A 1 measurement · score 0.26
- serum alanine aminotransferase measurement · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O14867-F1 | alphafold | PREDICTED | 56.48 | — |
Amino-acid sequence (736 residues)
MSLSENSVFA YESSVHSTNV LLSLNDQRKK DVLCDVTIFV EGQRFRAHRS VLAACSSYFH SRIVGQADGE LNITLPEEVT VKGFEPLIQF AYTAKLILSK ENVDEVCKCV EFLSVHNIEE SCFQFLKFKF LDSTADQQEC PRKKCFSSHC QKTDLKLSLL DQRDLETDEV EEFLENKNVQ TPQCKLRRYQ GNAKASPPLQ DSASQTYESM CLEKDAALAL PSLCPKYRKF QKAFGTDRVR TGESSVKDIH ASVQPNERSE NECLGGVPEC RDLQVMLKCD ESKLAMEPEE TKKDPASQCP TEKSEVTPFP HNSSIDPHGL YSLSLLHTYD QYGDLNFAGM QNTTVLTEKP LSGTDVQEKT FGESQDLPLK SDLGTREDSS VASSDRSSVE REVAEHLAKG FWSDICSTDT PCQMQLSPAV AKDGSEQISQ KRSECPWLGI RISESPEPGQ RTFTTLSSVN CPFISTLSTE GCSSNLEIGN DDYVSEPQQE PCPYACVISL GDDSETDTEG DSESCSAREQ ECEVKLPFNA QRIISLSRND FQSLLKMHKL TPEQLDCIHD IRRRSKNRIA AQRCRKRKLD CIQNLESEIE KLQSEKESLL KERDHILSTL GETKQNLTGL CQKVCKEAAL SQEQIQILAK YSAADCPLSF LISEKDKSTP DGELALPSIF SLSDRPPAVL PPCARGNSEP GYARGQESQQ MSTATSEQAG PAEQCRQSGG ISDFCQQMTD KCTTDE
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