Protein Wnt-9a (WNT9A)

About Protein Wnt-9a

Protein Wnt-9a (WNT9A) is a protein from Homo sapiens identified by UniProt accession O14904, 365 residues long. MolForge cross-references it against 0 known binders and 106 disease associations.

Target properties

Protein name	Protein Wnt-9a
UniProt accession	O14904
Gene	WNT9A
Organism	Homo sapiens
Length	365 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (106)

Diseases linked to this target (Open Targets).

systolic blood pressure · score 0.40
body height · score 0.39
diastolic blood pressure · score 0.39
Moyamoya disease · score 0.26
Agents acting on the renin-angiotensin system use measurement · score 0.25
body weight · score 0.22
cardiovascular disease · score 0.21
high density lipoprotein cholesterol measurement · score 0.20
ovarian cancer · score 0.19
hypertension · score 0.18

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O14904-F1	alphafold	PREDICTED	82.27	—

Amino-acid sequence (365 residues)

MLDGSPLARW LAAAFGLTLL LAALRPSAAY FGLTGSEPLT ILPLTLEPEA AAQAHYKACD RLKLERKQRR MCRRDPGVAE TLVEAVSMSA LECQFQFRFE RWNCTLEGRY RASLLKRGFK ETAFLYAISS AGLTHALAKA CSAGRMERCT CDEAPDLENR EAWQWGGCGD NLKYSSKFVK EFLGRRSSKD LRARVDFHNN LVGVKVIKAG VETTCKCHGV SGSCTVRTCW RQLAPFHEVG KHLKHKYETA LKVGSTTNEA AGEAGAISPP RGRASGAGGS DPLPRTPELV HLDDSPSFCL AGRFSPGTAG RRCHREKNCE SICCGRGHNT QSRVVTRPCQ CQVRWCCYVE CRQCTQREEV YTCKG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards