About Protein Wnt-9b
Protein Wnt-9b (WNT9B) is a protein
from Homo sapiens identified by UniProt accession
O14905, 357 residues long.
MolForge cross-references it against 0 known binders and
179 disease associations.
Target properties
| Protein name | Protein Wnt-9b |
|---|
| UniProt accession | O14905 |
|---|
| Gene | WNT9B |
|---|
| Organism | Homo sapiens |
|---|
| Length | 357 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (179)
Diseases linked to this target (Open Targets).
- serum urea measurement · score 0.37
- bilateral renal agenesis · score 0.37
- intraocular pressure measurement · score 0.34
- chronic kidney disease · score 0.32
- vein disorder · score 0.30
- Varicose veins · score 0.30
- lymphatic system disease · score 0.30
- neurodegenerative disease · score 0.28
- renal dysplasia · score 0.27
- renal hypoplasia · score 0.26
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O14905-F1 | alphafold | PREDICTED | 83.61 | — |
Amino-acid sequence (357 residues)
MRPPPALALA GLCLLALPAA AASYFGLTGR EVLTPFPGLG TAAAPAQGGA HLKQCDLLKL SRRQKQLCRR EPGLAETLRD AAHLGLLECQ FQFRHERWNC SLEGRMGLLK RGFKETAFLY AVSSAALTHT LARACSAGRM ERCTCDDSPG LESRQAWQWG VCGDNLKYST KFLSNFLGSK RGNKDLRARA DAHNTHVGIK AVKSGLRTTC KCHGVSGSCA VRTCWKQLSP FRETGQVLKL RYDSAVKVSS ATNEALGRLE LWAPARQGSL TKGLAPRSGD LVYMEDSPSF CRPSKYSPGT AGRVCSREAS CSSLCCGRGY DTQSRLVAFS CHCQVQWCCY VECQQCVQEE LVYTCKH
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