Tax1-binding protein 3 (TAX1BP3)

About Tax1-binding protein 3

Tax1-binding protein 3 (TAX1BP3) is a protein from Homo sapiens identified by UniProt accession O14907, 124 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.

Target properties

Protein name	Tax1-binding protein 3
UniProt accession	O14907
Gene	TAX1BP3
Organism	Homo sapiens
Length	124 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (43)

Diseases linked to this target (Open Targets).

ocular cystinosis · score 0.18
nephropathic cystinosis · score 0.18
cystinosis · score 0.18
familial dilated cardiomyopathy · score 0.12
neoplasm · score 0.09
glioblastoma · score 0.08
Systemic lupus erythematosus · score 0.06
cancer · score 0.05
malignant glioma · score 0.04
Crigler-Najjar syndrome type 2 · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O14907-F1	alphafold	PREDICTED	91.25	—

Amino-acid sequence (124 residues)

MSYIPGQPVT AVVQRVEIHK LRQGENLILG FSIGGGIDQD PSQNPFSEDK TDKGIYVTRV SEGGPAEIAG LQIGDKIMQV NGWDMTMVTH DQARKRLTKR SEEVVRLLVT RQSLQKAVQQ SMLS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards