About Protein lin-7 homolog A
Protein lin-7 homolog A (LIN7A) is a protein
from Homo sapiens identified by UniProt accession
O14910, 233 residues long.
MolForge cross-references it against 0 known binders and
71 disease associations.
Target properties
| Protein name | Protein lin-7 homolog A |
|---|
| UniProt accession | O14910 |
|---|
| Gene | LIN7A |
|---|
| Organism | Homo sapiens |
|---|
| Length | 233 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (71)
Diseases linked to this target (Open Targets).
- type 2 diabetes mellitus · score 0.27
- neurodegenerative disease · score 0.26
- serum gamma-glutamyl transferase measurement · score 0.19
- gait measurement · score 0.11
- alcohol consumption measurement · score 0.08
- infection · score 0.07
- infect · score 0.07
- diet measurement · score 0.07
- alcohol use disorder measurement · score 0.05
- hepatocellular carcinoma · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O14910-F1 | alphafold | PREDICTED | 80.25 | — |
Amino-acid sequence (233 residues)
MLKPSVTSAP TADMATLTVV QPLTLDRDVA RAIELLEKLQ ESGEVPVHKL QSLKKVLQSE FCTAIREVYQ YMHETITVNG CPEFRARATA KATVAAFAAS EGHSHPRVVE LPKTDEGLGF NVMGGKEQNS PIYISRIIPG GVAERHGGLK RGDQLLSVNG VSVEGEHHEK AVELLKAAKD SVKLVVRYTP KVLEEMEARF EKLRTARRRQ QQQLLIQQQQ QQQQQQTQQN HMS
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