About Regulator of G-protein signaling 13
Regulator of G-protein signaling 13 (RGS13) is a protein
from Homo sapiens identified by UniProt accession
O14921, 159 residues long.
MolForge cross-references it against 0 known binders and
170 disease associations.
Target properties
| Protein name | Regulator of G-protein signaling 13 |
|---|
| UniProt accession | O14921 |
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| Gene | RGS13 |
|---|
| Organism | Homo sapiens |
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| Length | 159 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (170)
Diseases linked to this target (Open Targets).
- neuroblastoma · score 0.11
- self reported educational attainment · score 0.09
- common variable immunodeficiency · score 0.07
- isolated agammaglobulinemia · score 0.07
- immunodeficiency 72 with autoinflammation · score 0.06
- ICF syndrome · score 0.06
- BENTA disease · score 0.06
- classic Hodgkin lymphoma · score 0.06
- Hodgkins lymphoma · score 0.06
- severe combined immunodeficiency due to CARD11 deficiency · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O14921-F1 | alphafold | PREDICTED | 93.42 | — |
Amino-acid sequence (159 residues)
MSRRNCWICK MCRDESKRPP SNLTLEEVLQ WAQSFENLMA TKYGPVVYAA YLKMEHSDEN IQFWMACETY KKIASRWSRI SRAKKLYKIY IQPQSPREIN IDSSTRETII RNIQEPTETC FEEAQKIVYM HMERDSYPRF LKSEMYQKLL KTMQSNNSF
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