About Natural cytotoxicity triggering receptor 3
Natural cytotoxicity triggering receptor 3 (NCR3) is a protein
from Homo sapiens identified by UniProt accession
O14931, 201 residues long.
MolForge cross-references it against 0 known binders and
213 disease associations.
Target properties
| Protein name | Natural cytotoxicity triggering receptor 3 |
|---|
| UniProt accession | O14931 |
|---|
| Gene | NCR3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 201 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (213)
Diseases linked to this target (Open Targets).
- viral disease · score 0.37
- complement C4 measurement · score 0.23
- visual perception measurement · score 0.22
- FEV/FVC ratio · score 0.13
- mathematical ability · score 0.13
- neoplasm · score 0.11
- self reported educational attainment · score 0.10
- pulmonary function measurement · score 0.10
- platelet count · score 0.10
- platelet crit · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O14931-F1 | alphafold | PREDICTED | 83.58 | — |
Amino-acid sequence (201 residues)
MAWMLLLILI MVHPGSCALW VSQPPEIRTL EGSSAFLPCS FNASQGRLAI GSVTWFRDEV VPGKEVRNGT PEFRGRLAPL ASSRFLHDHQ AELHIRDVRG HDASIYVCRV EVLGLGVGTG NGTRLVVEKE HPQLGAGTVL LLRAGFYAVS FLSVAVGSTV YYQGKCLTWK GPRRQLPAVV PAPLPPPCGS SAHLLPPVPG G
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