Leukocyte cell-derived chemotaxin-2 (LECT2)

About Leukocyte cell-derived chemotaxin-2

Leukocyte cell-derived chemotaxin-2 (LECT2) is a protein from Homo sapiens identified by UniProt accession O14960, 151 residues long. MolForge cross-references it against 0 known binders and 137 disease associations.

Target properties

Protein name	Leukocyte cell-derived chemotaxin-2
UniProt accession	O14960
Gene	LECT2
Organism	Homo sapiens
Length	151 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (137)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.36
body height · score 0.31
neurodegenerative disease · score 0.31
eosinophil count · score 0.23
hepatocellular carcinoma · score 0.12
neoplasm · score 0.11
non-alcoholic fatty liver disease · score 0.09
inherited lipid metabolism disorder · score 0.07
type 2 diabetes mellitus · score 0.06
metabolic syndrome · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O14960-F1	alphafold	PREDICTED	92.45	—

Amino-acid sequence (151 residues)

MFSTKALLLA GLISTALAGP WANICAGKSS NEIRTCDRHG CGQYSAQRSQ RPHQGVDILC SAGSTVYAPF TGMIVGQEKP YQNKNAINNG VRISGRGFCV KMFYIKPIKY KGPIKKGEKL GTLLPLQKVY PGIQSHVHIE NCDSSDPTAY L

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards