About Ras-related protein Rab-29
Ras-related protein Rab-29 (RAB29) is a protein
from Homo sapiens identified by UniProt accession
O14966, 203 residues long.
MolForge cross-references it against 0 known binders and
80 disease associations.
Target properties
| Protein name | Ras-related protein Rab-29 |
|---|
| UniProt accession | O14966 |
|---|
| Gene | RAB29 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 203 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (80)
Diseases linked to this target (Open Targets).
- body height · score 0.33
- Parkinson disease · score 0.31
- alkaline phosphatase measurement · score 0.30
- body weight · score 0.27
- prostate carcinoma · score 0.25
- monocyte percentage of leukocytes · score 0.24
- high density lipoprotein cholesterol measurement · score 0.23
- HbA1c measurement · score 0.23
- uric acid measurement · score 0.21
- lean body mass · score 0.20
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O14966-F1 | alphafold | PREDICTED | 88.61 | — |
Amino-acid sequence (203 residues)
MGSRDHLFKV LVVGDAAVGK TSLVQRYSQD SFSKHYKSTV GVDFALKVLQ WSDYEIVRLQ LWDIAGQERF TSMTRLYYRD ASACVIMFDV TNATTFSNSQ RWKQDLDSKL TLPNGEPVPC LLLANKCDLS PWAVSRDQID RFSKENGFTG WTETSVKENK NINEAMRVLI EKMMRNSTED IMSLSTQGDY INLQTKSSSW SCC
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