About Long-chain fatty acid transport protein 2
Long-chain fatty acid transport protein 2 (SLC27A2) is a protein
from Homo sapiens identified by UniProt accession
O14975, 620 residues long.
MolForge cross-references it against 0 known binders and
132 disease associations.
Target properties
| Protein name | Long-chain fatty acid transport protein 2 |
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| UniProt accession | O14975 |
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| Gene | SLC27A2 |
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| Organism | Homo sapiens |
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| Length | 620 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (132)
Diseases linked to this target (Open Targets).
- blood metabolite measurement · score 0.28
- monocyte count · score 0.21
- platelet count · score 0.12
- neoplasm · score 0.10
- mean platelet volume · score 0.10
- FEV/FVC ratio · score 0.09
- basophil count · score 0.08
- diffuse large B-cell lymphoma · score 0.08
- acute lymphoblastic leukemia · score 0.08
- nonpapillary renal cell carcinoma · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O14975-F1 | alphafold | PREDICTED | 92.24 | — |
Amino-acid sequence (620 residues)
MLSAIYTVLA GLLFLPLLVN LCCPYFFQDI GYFLKVAAVG RRVRSYGKRR PARTILRAFL EKARQTPHKP FLLFRDETLT YAQVDRRSNQ VARALHDHLG LRQGDCVALL MGNEPAYVWL WLGLVKLGCA MACLNYNIRA KSLLHCFQCC GAKVLLVSPE LQAAVEEILP SLKKDDVSIY YVSRTSNTDG IDSFLDKVDE VSTEPIPESW RSEVTFSTPA LYIYTSGTTG LPKAAMITHQ RIWYGTGLTF VSGLKADDVI YITLPFYHSA ALLIGIHGCI VAGATLALRT KFSASQFWDD CRKYNVTVIQ YIGELLRYLC NSPQKPNDRD HKVRLALGNG LRGDVWRQFV KRFGDICIYE FYAATEGNIG FMNYARKVGA VGRVNYLQKK IITYDLIKYD VEKDEPVRDE NGYCVRVPKG EVGLLVCKIT QLTPFNGYAG AKAQTEKKKL RDVFKKGDLY FNSGDLLMVD HENFIYFHDR VGDTFRWKGE NVATTEVADT VGLVDFVQEV NVYGVHVPDH EGRIGMASIK MKENHEFDGK KLFQHIADYL PSYARPRFLR IQDTIEITGT FKHRKMTLVE EGFNPAVIKD ALYFLDDTAK MYVPMTEDIY NAISAKTLKL
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