About Zinc finger protein 263
Zinc finger protein 263 (ZNF263) is a protein
from Homo sapiens identified by UniProt accession
O14978, 683 residues long.
MolForge cross-references it against 0 known binders and
36 disease associations.
Target properties
| Protein name | Zinc finger protein 263 |
|---|
| UniProt accession | O14978 |
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| Gene | ZNF263 |
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| Organism | Homo sapiens |
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| Length | 683 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (36)
Diseases linked to this target (Open Targets).
- serum gamma-glutamyl transferase measurement · score 0.23
- serum alanine aminotransferase measurement · score 0.21
- vital capacity · score 0.19
- attention deficit hyperactivity disorder · score 0.15
- substance abuse · score 0.15
- antisocial behaviour measurement · score 0.15
- diastolic blood pressure · score 0.14
- IGF-1 measurement · score 0.11
- waist-hip ratio · score 0.11
- hepatocellular carcinoma · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O14978-F1 | alphafold | PREDICTED | 60.24 | — |
Amino-acid sequence (683 residues)
MASGPGSQER EGLLIVKLEE DCAWSQELPP PDPGPSPEAS HLRFRRFRFQ EAAGPREALS RLQELCHGWL RPEMRTKEQI LELLVLEQFL TILPQEIQSR VQELHPESGE EAVTLVEDMQ RELGRLRQQV TNHGRGTEVL LEEPLPLETA RESPSFKLEP METERSPGPR LQELLGPSPQ RDPQAVKERA LSAPWLSLFP PEGNMEDKEM TGPQLPESLE DVAMYISQEE WGHQDPSKRA LSRDTVQESY ENVDSLESHI PSQEVPGTQV GQGGKLWDPS VQSCKEGLSP RGPAPGEEKF ENLEGVPSVC SENIHPQVLL PDQARGEVPW SPELGRPHDR SQGDWAPPPE GGMEQALAGA SSGRELGRPK ELQPKKLHLC PLCGKNFSNN SNLIRHQRIH AAERLCMGVD CTEIFGGNPR FLSLHRAHLG EEAHKCLECG KCFSQNTHLT RHQRTHTGEK PYQCNICGKC FSCNSNLHRH QRTHTGEKPY KCPECGEIFA HSSNLLRHQR IHTGERPYKC PECGKSFSRS SHLVIHERTH ERERLYPFSE CGEAVSDSTP FLTNHGAHKA EKKLFECLTC GKSFRQGMHL TRHQRTHTGE KPYKCTLCGE NFSHRSNLIR HQRIHTGEKP YTCHECGDSF SHSSNRIRHL RTHTGERPYK CSECGESFSR SSRLMSHQRT HTG
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