About Protein KHNYN
Protein KHNYN (KHNYN) is a protein
from Homo sapiens identified by UniProt accession
O15037, 678 residues long.
MolForge cross-references it against 0 known binders and
25 disease associations.
Target properties
| Protein name | Protein KHNYN |
|---|
| UniProt accession | O15037 |
|---|
| Gene | KHNYN |
|---|
| Organism | Homo sapiens |
|---|
| Length | 678 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (25)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- sex hormone-binding globulin measurement · score 0.20
- appendicular lean mass · score 0.20
- cortical surface area measurement · score 0.20
- body height · score 0.18
- Red cell distribution width · score 0.16
- brain measurement · score 0.16
- diet measurement · score 0.13
- mean platelet volume · score 0.12
- genetic disorder · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O15037-F1 | alphafold | PREDICTED | 67.83 | — |
Amino-acid sequence (678 residues)
MPTWGARPAS PDRFAVSAEA ENKVREQQPH VERIFSVGVS VLPKDCPDNP HIWLQLEGPK ENASRAKEYL KGLCSPELQD EIHYPPKLHC IFLGAQGFFL DCLAWSTSAH LVPRAPGSLM ISGLTEAFVM AQSRVEELAE RLSWDFTPGP SSGASQCTGV LRDFSALLQS PGDAHREALL QLPLAVQEEL LSLVQEASSG QGPGALASWE GRSSALLGAQ CQGVRAPPSD GRESLDTGSM GPGDCRGARG DTYAVEKEGG KQGGPREMDW GWKELPGEEA WEREVALRPQ SVGGGARESA PLKGKALGKE EIALGGGGFC VHREPPGAHG SCHRAAQSRG ASLLQRLHNG NASPPRVPSP PPAPEPPWHC GDRGDCGDRG DVGDRGDKQQ GMARGRGPQW KRGARGGNLV TGTQRFKEAL QDPFTLCLAN VPGQPDLRHI VIDGSNVAMV HGLQHYFSSR GIAIAVQYFW DRGHRDITVF VPQWRFSKDA KVRESHFLQK LYSLSLLSLT PSRVMDGKRI SSYDDRFMVK LAEETDGIIV SNDQFRDLAE ESEKWMAIIR ERLLPFTFVG NLFMVPDDPL GRNGPTLDEF LKKPARTQGS SKAQHPSRGF AEHGKQQQGR EEEKGSGGIR KTRETERLRR QLLEVFWGQD HKVDFILQRE PYCRDINQLS EALLSLNF
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