About Secretory carrier-associated membrane protein 1
Secretory carrier-associated membrane protein 1 (SCAMP1) is a protein
from Homo sapiens identified by UniProt accession
O15126, 338 residues long.
MolForge cross-references it against 0 known binders and
53 disease associations.
Target properties
| Protein name | Secretory carrier-associated membrane protein 1 |
|---|
| UniProt accession | O15126 |
|---|
| Gene | SCAMP1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 338 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (53)
Diseases linked to this target (Open Targets).
- platelet count · score 0.44
- platelet crit · score 0.41
- mathematical ability · score 0.33
- platelet component distribution width · score 0.29
- adolescent idiopathic scoliosis · score 0.27
- intraocular pressure measurement · score 0.26
- unipolar depression · score 0.23
- bipolar disorder · score 0.23
- serum gamma-glutamyl transferase measurement · score 0.07
- acute myeloid leukemia · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O15126-F1 | alphafold | PREDICTED | 79.02 | — |
Amino-acid sequence (338 residues)
MSDFDSNPFA DPDLNNPFKD PSVTQVTRNV PPGLDEYNPF SDSRTPPPGG VKMPNVPNTQ PAIMKPTEEH PAYTQIAKEH ALAQAELLKR QEELERKAAE LDRREREMQN LSQHGRKNNW PPLPSNFPVG PCFYQDFSVD IPVEFQKTVK LMYYLWMFHA VTLFLNIFGC LAWFCVDSAR AVDFGLSILW FLLFTPCSFV CWYRPLYGAF RSDSSFRFFV FFFVYICQFA VHVLQAAGFH NWGNCGWISS LTGLNQNIPV GIMMIIIAAL FTASAVISLV MFKKVHGLYR TTGASFEKAQ QEFATGVMSN KTVQTAAANA ASTAASSAAQ NAFKGNQI
Explore Secretory carrier-associated membrane protein 1 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets