About Secretory carrier-associated membrane protein 2
Secretory carrier-associated membrane protein 2 (SCAMP2) is a protein
from Homo sapiens identified by UniProt accession
O15127, 329 residues long.
MolForge cross-references it against 0 known binders and
92 disease associations.
Target properties
| Protein name | Secretory carrier-associated membrane protein 2 |
|---|
| UniProt accession | O15127 |
|---|
| Gene | SCAMP2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 329 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (92)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.16
- mean corpuscular hemoglobin · score 0.15
- diastolic blood pressure · score 0.14
- systolic blood pressure · score 0.13
- alcohol drinking · score 0.13
- platelet count · score 0.11
- smoking status measurement · score 0.11
- mean arterial pressure · score 0.10
- total cholesterol measurement · score 0.10
- neutrophil percentage of leukocytes · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O15127-F1 | alphafold | PREDICTED | 76.32 | — |
Amino-acid sequence (329 residues)
MSAFDTNPFA DPVDVNPFQD PSVTQLTNAP QGGLAEFNPF SETNAATTVP VTQLPGSSQP AVLQPSVEPT QPTPQAVVSA AQAGLLRQQE ELDRKAAELE RKERELQNTV ANLHVRQNNW PPLPSWCPVK PCFYQDFSTE IPADYQRICK MLYYLWMLHS VTLFLNLLAC LAWFSGNSSK GVDFGLSILW FLIFTPCAFL CWYRPIYKAF RSDNSFSFFV FFFVFFCQIG IYIIQLVGIP GLGDSGWIAA LSTLDNHSLA ISVIMMVVAG FFTLCAVLSV FLLQRVHSLY RRTGASFQQA QEEFSQGIFS SRTFHRAASS AAQGAFQGN
Explore Secretory carrier-associated membrane protein 2 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets