About Actin-related protein 2/3 complex subunit 3
Actin-related protein 2/3 complex subunit 3 (ARPC3) is a protein
from Homo sapiens identified by UniProt accession
O15145, 178 residues long.
MolForge cross-references it against 0 known binders and
60 disease associations.
Target properties
| Protein name | Actin-related protein 2/3 complex subunit 3 |
|---|
| UniProt accession | O15145 |
|---|
| Gene | ARPC3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 178 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (60)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.55
- cutaneous Leishmaniasis · score 0.37
- neuroinflammatory disorder · score 0.37
- lysosomal storage disease · score 0.26
- Alzheimer disease · score 0.26
- Parkinson disease · score 0.26
- multiple sclerosis · score 0.26
- environmental tobacco smoke exposure measurement · score 0.23
- body mass index · score 0.08
- red blood cell density measurement · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O15145-F1 | alphafold | PREDICTED | 95.06 | — |
Amino-acid sequence (178 residues)
MPAYHSSLMD PDTKLIGNMA LLPIRSQFKG PAPRETKDTD IVDEAIYYFK ANVFFKNYEI KNEADRTLIY ITLYISECLK KLQKCNSKSQ GEKEMYTLGI TNFPIPGEPG FPLNAIYAKP ANKQEDEVMR AYLQQLRQET GLRLCEKVFD PQNDKPSKWW TCFVKRQFMN KSLSGPGQ
Explore Actin-related protein 2/3 complex subunit 3 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets