BET1 homolog (BET1)

About BET1 homolog

BET1 homolog (BET1) is a protein from Homo sapiens identified by UniProt accession O15155, 118 residues long. MolForge cross-references it against 0 known binders and 45 disease associations.

Target properties

Protein name	BET1 homolog
UniProt accession	O15155
Gene	BET1
Organism	Homo sapiens
Length	118 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (45)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.55
muscular dystrophy, congenital, with rapid progression · score 0.55
blood protein measurement · score 0.31
congenital muscular dystrophy · score 0.18
Progressive muscle weakness · score 0.15
Seizure · score 0.15
diastolic blood pressure · score 0.04
neoplasm · score 0.02
cancer · score 0.01
non-small cell lung carcinoma · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O15155-F1	alphafold	PREDICTED	83.09	—

Amino-acid sequence (118 residues)

MRRAGLGEGV PPGNYGNYGY ANSGYSACEE ENERLTESLR SKVTAIKSLS IEIGHEVKTQ NKLLAEMDSQ FDSTTGFLGK TMGKLKILSR GSQTKLLCYM MLFSLFVFFI IYWIIKLR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards