Zinc finger and BTB domain-containing protein 7B (ZBTB7B)

Homo sapiens — UniProt O15156

Gene: ZBTB7BHomo sapiensSwissProt reviewed

About Zinc finger and BTB domain-containing protein 7B

Zinc finger and BTB domain-containing protein 7B (ZBTB7B) is a protein from Homo sapiens identified by UniProt accession O15156, 539 residues long. MolForge cross-references it against 0 known binders and 144 disease associations.

Target properties

Protein nameZinc finger and BTB domain-containing protein 7B
UniProt accessionO15156
GeneZBTB7B
OrganismHomo sapiens
Length539 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-O15156-F1alphafoldPREDICTED55.09—

Amino-acid sequence (539 residues)

MGSPEDDLIG IPFPDHSSEL LSCLNEQRQL GHLCDLTIRT QGLEYRTHRA VLAACSHYFK KLFTEGGGGA VMGAGGSGTA TGGAGAGVCE LDFVGPEALG ALLEFAYTAT LTTSSANMPA VLQAARLLEI PCVIAACMEI LQGSGLEAPS PDEDDCERAR QYLEAFATAT ASGVPNGEDS PPQVPLPPPP PPPPRPVARR SRKPRKAFLQ TKGARANHLV PEVPTVPAHP LTYEEEEVAG RVGSSGGSGP GDSYSPPTGT ASPPEGPQSY EPYEGEEEEE ELVYPPAYGL AQGGGPPLSP EELGSDEDAI DPDLMAYLSS LHQDNLAPGL DSQDKLVRKR RSQMPQECPV CHKIIHGAGK LPRHMRTHTG EKPFACEVCG VRFTRNDKLK IHMRKHTGER PYSCPHCPAR FLHSYDLKNH MHLHTGDRPY ECHLCHKAFA KEDHLQRHLK GQNCLEVRTR RRRKDDAPPH YPPPSTAAAS PAGLDLSNGH LDTFRLSLAR FWEQSAPTGP PVSTPGPPDD DEEEGAPTTP QAEGAMESS

Explore Zinc finger and BTB domain-containing protein 7B with MolForge

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Quick facts

UniProtO15156
GeneZBTB7B
OrganismHomo sapiens
Length539
Binders0
Diseases144
View on UniProt