About Centrin-3
Centrin-3 (CETN3) is a protein
from Homo sapiens identified by UniProt accession
O15182, 167 residues long.
MolForge cross-references it against 0 known binders and
41 disease associations.
Target properties
| Protein name | Centrin-3 |
|---|
| UniProt accession | O15182 |
|---|
| Gene | CETN3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 167 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (41)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.34
- daytime rest measurement · score 0.28
- diastolic blood pressure · score 0.23
- insulin like growth factor measurement · score 0.19
- IGF-1 measurement · score 0.19
- intelligence · score 0.16
- white matter microstructure measurement · score 0.13
- refractive error · score 0.13
- schizophrenia · score 0.12
- creatinine measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O15182-F1 | alphafold | PREDICTED | 88.98 | — |
Amino-acid sequence (167 residues)
MSLALRSELV VDKTKRKKRR ELSEEQKQEI KDAFELFDTD KDEAIDYHEL KVAMRALGFD VKKADVLKIL KDYDREATGK ITFEDFNEVV TDWILERDPH EEILKAFKLF DDDDSGKISL RNLRRVAREL GENMSDEELR AMIEEFDKDG DGEINQEEFI AIMTGDI
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