CTD small phosphatase-like protein (CTDSPL)

About CTD small phosphatase-like protein

CTD small phosphatase-like protein (CTDSPL) is a protein from Homo sapiens identified by UniProt accession O15194, 276 residues long. MolForge cross-references it against 0 known binders and 83 disease associations.

Target properties

Protein name	CTD small phosphatase-like protein
UniProt accession	O15194
Gene	CTDSPL
Organism	Homo sapiens
Length	276 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (83)

Diseases linked to this target (Open Targets).

erythrocyte count · score 0.32
disorder of pilosebaceous unit · score 0.30
Epidermal Inclusion Cyst · score 0.29
lymphocyte count · score 0.28
red blood cell density measurement · score 0.28
hematocrit · score 0.27
hemoglobin measurement · score 0.27
monocyte count · score 0.25
mean platelet volume · score 0.22
mean corpuscular hemoglobin concentration · score 0.22

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O15194-F1	alphafold	PREDICTED	77.77	—

Amino-acid sequence (276 residues)

MDGPAIITQV TNPKEDEGRL PGAGEKASQC NVSLKKQRSR SILSSFFCCF RDYNVEAPPP SSPSVLPPLV EENGGLQKGD QRQVIPIPSP PAKYLLPEVT VLDYGKKCVV IDLDETLVHS SFKPISNADF IVPVEIDGTI HQVYVLKRPH VDEFLQRMGQ LFECVLFTAS LAKYADPVAD LLDRWGVFRA RLFRESCVFH RGNYVKDLSR LGRELSKVII VDNSPASYIF HPENAVPVQS WFDDMTDTEL LDLIPFFEGL SREDDVYSML HRLCNR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards