ADAM DEC1 (ADAMDEC1)

About ADAM DEC1

ADAM DEC1 (ADAMDEC1) is a protein from Homo sapiens identified by UniProt accession O15204, 470 residues long. MolForge cross-references it against 0 known binders and 199 disease associations.

Target properties

Protein name	ADAM DEC1
UniProt accession	O15204
Gene	ADAMDEC1
Organism	Homo sapiens
Length	470 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (199)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.38
inflammatory bowel disease · score 0.10
non-small cell lung carcinoma · score 0.08
glioblastoma multiforme · score 0.07
body height · score 0.07
Autosomal recessive early-onset inflammatory bowel disease · score 0.07
central nervous system cancer · score 0.06
neoplasm · score 0.06
isolated agammaglobulinemia · score 0.06
Immunodeficiency by defective expression of HLA class 2 · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O15204-F1	alphafold	PREDICTED	80.18	—

Amino-acid sequence (470 residues)

MLRGISQLPA VATMSWVLLP VLWLIVQTQA IAIKQTPELT LHEIVCPKKL HILHKREIKN NQTEKHGKEE RYEPEVQYQM ILNGEEIILS LQKTKHLLGP DYTETLYSPR GEEITTKPEN MEHCYYKGNI LNEKNSVASI STCDGLRGYF THHHQRYQIK PLKSTDEKEH AVFTSNQEEQ DPANHTCGVK STDGKQGPIR ISRSLKSPEK EDFLRAQKYI DLYLVLDNAF YKNYNENLTL IRSFVFDVMN LLNVIYNTID VQVALVGMEI WSDGDKIKVV PSASTTFDNF LRWHSSNLGK KIHDHAQLLS GISFNNRRVG LAASNSLCSP SSVAVIEAKK KNNVALVGVM SHELGHVLGM PDVPFNTKCP SGSCVMNQYL SSKFPKDFST SCRAHFERYL LSQKPKCLLQ APIPTNIMTT PVCGNHLLEV GEDCDCGSPK ECTNLCCEAL TCKLKPGTDC GGDAPNHTTE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards