Ubiquitin D (UBD)

Homo sapiens — UniProt O15205

Gene: UBDHomo sapiensSwissProt reviewed

About Ubiquitin D

Ubiquitin D (UBD) is a protein from Homo sapiens identified by UniProt accession O15205, 165 residues long. MolForge cross-references it against 0 known binders and 178 disease associations.

Target properties

Protein nameUbiquitin D
UniProt accessionO15205
GeneUBD
OrganismHomo sapiens
Length165 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (178)

Diseases linked to this target (Open Targets).

  • body height · score 0.25
  • schizophrenia · score 0.21
  • mean corpuscular hemoglobin · score 0.13
  • mean corpuscular volume · score 0.12
  • hepatocellular carcinoma · score 0.11
  • neoplasm · score 0.11
  • breast cancer · score 0.08
  • lung carcinoma · score 0.08
  • cancer · score 0.08
  • myocardial infarction · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-O15205-F1alphafoldPREDICTED85.02—

Amino-acid sequence (165 residues)

MAPNASCLCV HVRSEEWDLM TFDANPYDSV KKIKEHVRSK TKVPVQDQVL LLGSKILKPR RSLSSYGIDK EKTIHLTLKV VKPSDEELPL FLVESGDEAK RHLLQVRRSS SVAQVKAMIE TKTGIIPETQ IVTCNGKRLE DGKMMADYGI RKGNLLFLAC YCIGG

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Quick facts

UniProtO15205
GeneUBD
OrganismHomo sapiens
Length165
Binders0
Diseases178
View on UniProt