About Protein RER1
Protein RER1 (RER1) is a protein
from Homo sapiens identified by UniProt accession
O15258, 196 residues long.
MolForge cross-references it against 0 known binders and
69 disease associations.
Target properties
| Protein name | Protein RER1 |
|---|
| UniProt accession | O15258 |
|---|
| Gene | RER1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 196 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (69)
Diseases linked to this target (Open Targets).
- vitamin D measurement · score 0.24
- alkaline phosphatase measurement · score 0.23
- peroxisome biogenesis disorder 6A (Zellweger) · score 0.19
- Peroxisome biogenesis disorder-Zellweger syndrome spectrum · score 0.19
- vitamin C measurement · score 0.16
- peroxisome biogenesis disorder 1A (Zellweger) · score 0.12
- pachyonychia congenita · score 0.07
- exercise intolerance, riboflavin-responsive · score 0.04
- protein measurement · score 0.04
- Distal myopathy, Nonaka type · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O15258-F1 | alphafold | PREDICTED | 78.59 | — |
Amino-acid sequence (196 residues)
MSEGDSVGES VHGKPSVVYR FFTRLGQIYQ SWLDKSTPYT AVRWVVTLGL SFVYMIRVYL LQGWYIVTYA LGIYHLNLFI AFLSPKVDPS LMEDSDDGPS LPTKQNEEFR PFIRRLPEFK FWHAATKGIL VAMVCTFFDA FNVPVFWPIL VMYFIMLFCI TMKRQIKHMI KYRYIPFTHG KRRYRGKEDA GKAFAS
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