Monocarboxylate transporter 7 (SLC16A6)

About Monocarboxylate transporter 7

Monocarboxylate transporter 7 (SLC16A6) is a protein from Homo sapiens identified by UniProt accession O15403, 523 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.

Target properties

Protein name	Monocarboxylate transporter 7
UniProt accession	O15403
Gene	SLC16A6
Organism	Homo sapiens
Length	523 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (43)

Diseases linked to this target (Open Targets).

body height · score 0.32
sodium measurement · score 0.22
chloride measurement · score 0.22
mean corpuscular volume · score 0.20
glucuronate measurement · score 0.13
high density lipoprotein cholesterol measurement · score 0.08
Limb dystonia · score 0.04
Barrett's esophagus · score 0.03
type 1 diabetes mellitus · score 0.02
acute quadriplegic myopathy · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O15403-F1	alphafold	PREDICTED	76.42	—

Amino-acid sequence (523 residues)

MTQNKLKLCS KANVYTEVPD GGWGWAVAVS FFFVEVFTYG IIKTFGVFFN DLMDSFNESN SRISWIISIC VFVLTFSAPL ATVLSNRFGH RLVVMLGGLL VSTGMVAASF SQEVSHMYVA IGIISGLGYC FSFLPTVTIL SQYFGKRRSI VTAVASTGEC FAVFAFAPAI MALKERIGWR YSLLFVGLLQ LNIVIFGALL RPIFIRGPAS PKIVIQENRK EAQYMLENEK TRTSIDSIDS GVELTTSPKN VPTHTNLELE PKADMQQVLV KTSPRPSEKK APLLDFSILK EKSFICYALF GLFATLGFFA PSLYIIPLGI SLGIDQDRAA FLLSTMAIAE VFGRIGAGFV LNREPIRKIY IELICVILLT VSLFAFTFAT EFWGLMSCSI FFGFMVGTIG GTHIPLLAED DVVGIEKMSS AAGVYIFIQS IAGLAGPPLA GLLVDQSKIY SRAFYSCAAG MALAAVCLAL VRPCKMGLCQ HHHSGETKVV SHRGKTLQDI PEDFLEMDLA KNEHRVHVQM EPV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards