Protein SLC31A2 (SLC31A2)

Homo sapiens — UniProt O15432

Gene: SLC31A2Homo sapiensSwissProt reviewed

About Protein SLC31A2

Protein SLC31A2 (SLC31A2) is a protein from Homo sapiens identified by UniProt accession O15432, 143 residues long. MolForge cross-references it against 0 known binders and 52 disease associations.

Target properties

Protein nameProtein SLC31A2
UniProt accessionO15432
GeneSLC31A2
OrganismHomo sapiens
Length143 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (52)

Diseases linked to this target (Open Targets).

  • mean corpuscular volume · score 0.37
  • mean corpuscular hemoglobin concentration · score 0.27
  • myeloid white cell count · score 0.27
  • mean corpuscular hemoglobin · score 0.21
  • mean reticulocyte volume · score 0.20
  • neutrophil count · score 0.15
  • sum of basophil and neutrophil counts · score 0.15
  • reticulocyte measurement · score 0.14
  • sum of neutrophil and eosinophil counts · score 0.11
  • granulocyte count · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-O15432-F1alphafoldPREDICTED71.84—

Amino-acid sequence (143 residues)

MAMHFIFSDT AVLLFDFWSV HSPAGMALSV LVLLLLAVLY EGIKVGKAKL LNQVLVNLPT SISQQTIAET DGDSAGSDSF PVGRTHHRWY LCHFGQSLIH VIQVVIGYFI MLAVMSYNTW IFLGVVLGSA VGYYLAYPLL STA

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Quick facts

UniProtO15432
GeneSLC31A2
OrganismHomo sapiens
Length143
Binders0
Diseases52
View on UniProt