C-C motif chemokine 25 (CCL25)

About C-C motif chemokine 25

C-C motif chemokine 25 (CCL25) is a protein from Homo sapiens identified by UniProt accession O15444, 150 residues long. MolForge cross-references it against 0 known binders and 217 disease associations.

Target properties

Protein name	C-C motif chemokine 25
UniProt accession	O15444
Gene	CCL25
Organism	Homo sapiens
Length	150 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (217)

Diseases linked to this target (Open Targets).

CCL25 measurement · score 0.42
blood protein measurement · score 0.28
protein measurement · score 0.26
C-C motif chemokine 25 measurement · score 0.18
breast adenocarcinoma · score 0.17
head and neck squamous cell carcinoma · score 0.17
neoplasm · score 0.10
endometriosis · score 0.08
Rheumatoid arthritis · score 0.07
triple-negative breast cancer · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O15444-F1	alphafold	PREDICTED	70.24	—

Amino-acid sequence (150 residues)

MNLWLLACLV AGFLGAWAPA VHTQGVFEDC CLAYHYPIGW AVLRRAWTYR IQEVSGSCNL PAAIFYLPKR HRKVCGNPKS REVQRAMKLL DARNKVFAKL HHNTQTFQAG PHAVKKLSSG NSKLSSSKFS NPISSSKRNV SLLISANSGL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards