C-C motif chemokine 16 (CCL16)

About C-C motif chemokine 16

C-C motif chemokine 16 (CCL16) is a protein from Homo sapiens identified by UniProt accession O15467, 120 residues long. MolForge cross-references it against 0 known binders and 89 disease associations.

Target properties

Protein name	C-C motif chemokine 16
UniProt accession	O15467
Gene	CCL16
Organism	Homo sapiens
Length	120 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (89)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.26
C-C motif chemokine 16 measurement · score 0.21
protein measurement · score 0.17
CCL23 measurement · score 0.15
hepatocellular carcinoma · score 0.07
neoplasm · score 0.06
C-C motif chemokine 14 measurement · score 0.06
endometriosis · score 0.05
cancer · score 0.04
irritable bowel syndrome · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O15467-F1	alphafold	PREDICTED	78.93	—

Amino-acid sequence (120 residues)

MKVSEAALSL LVLILIITSA SRSQPKVPEW VNTPSTCCLK YYEKVLPRRL VVGYRKALNC HLPAIIFVTK RNREVCTNPN DDWVQEYIKD PNLPLLPTRN LSTVKIITAK NGQPQLLNSQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards