About Regulator of G-protein signaling 16
Regulator of G-protein signaling 16 (RGS16) is a protein
from Homo sapiens identified by UniProt accession
O15492, 202 residues long.
MolForge cross-references it against 0 known binders and
119 disease associations.
Target properties
| Protein name | Regulator of G-protein signaling 16 |
|---|
| UniProt accession | O15492 |
|---|
| Gene | RGS16 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 202 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (119)
Diseases linked to this target (Open Targets).
- chronotype measurement · score 0.42
- circadian rhythm · score 0.35
- DNA methylation · score 0.25
- physical activity measurement · score 0.21
- sleep duration · score 0.16
- excessive daytime sleepiness measurement · score 0.16
- insomnia measurement · score 0.16
- ulcerative colitis · score 0.08
- neoplasm · score 0.08
- pancreatic neoplasm · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O15492-F1 | alphafold | PREDICTED | 81.74 | — |
Amino-acid sequence (202 residues)
MCRTLAAFPT TCLERAKEFK TRLGIFLHKS ELGCDTGSTG KFEWGSKHSK ENRNFSEDVL GWRESFDLLL SSKNGVAAFH AFLKTEFSEE NLEFWLACEE FKKIRSATKL ASRAHQIFEE FICSEAPKEV NIDHETHELT RMNLQTATAT CFDAAQGKTR TLMEKDSYPR FLKSPAYRDL AAQASAASAT LSSCSLDEPS HT
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