Homeobox protein goosecoid-2 (GSC2)

About Homeobox protein goosecoid-2

Homeobox protein goosecoid-2 (GSC2) is a protein from Homo sapiens identified by UniProt accession O15499, 205 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.

Target properties

Protein name	Homeobox protein goosecoid-2
UniProt accession	O15499
Gene	GSC2
Organism	Homo sapiens
Length	205 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (9)

Diseases linked to this target (Open Targets).

systemic scleroderma · score 0.09
platelet crit · score 0.05
22q11.2 deletion syndrome · score 0.03
drug use measurement · score 0.03
Down syndrome · score 0.01
psychiatric disorder · score 0.00
learning disability · score 0.00
schizophrenia · score 0.00
gonorrhea · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O15499-F1	alphafold	PREDICTED	67.31	—

Amino-acid sequence (205 residues)

MAAAAGGAAS RRGAGRPCPF SIEHILSSLP ERSLPARAAC PPQPAGRQSP AKPEEPGAPE AAPCACCCCC GPRAAPCGPP EAAAGLGARL AWPLRLGPAV PLSLGAPAGG SGALPGAVGP GSQRRTRRHR TIFSEEQLQA LEALFVQNQY PDVSTRERLA GRIRLREERV EVWFKNRRAK WRHQKRASAS ARLLPGVKKS PKGSC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards