About Fibroblast growth factor 10
Fibroblast growth factor 10 (FGF10) is a protein
from Homo sapiens identified by UniProt accession
O15520, 208 residues long.
MolForge cross-references it against 0 known binders and
610 disease associations.
Target properties
| Protein name | Fibroblast growth factor 10 |
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| UniProt accession | O15520 |
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| Gene | FGF10 |
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| Organism | Homo sapiens |
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| Length | 208 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (610)
Diseases linked to this target (Open Targets).
- LADD syndrome · score 0.74
- aplasia of lacrimal and salivary glands · score 0.65
- lacrimoauriculodentodigital syndrome 3 · score 0.64
- cancer · score 0.61
- Lacrimoauriculodentodigital syndrome · score 0.60
- bone development disease · score 0.58
- female reproductive endometrioid cancer · score 0.50
- vital capacity · score 0.48
- ovarian carcinoma · score 0.46
- forced expiratory volume · score 0.45
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O15520-F1 | alphafold | PREDICTED | 80.01 | — |
Amino-acid sequence (208 residues)
MWKWILTHCA SAFPHLPGCC CCCFLLLFLV SSVPVTCQAL GQDMVSPEAT NSSSSSFSSP SSAGRHVRSY NHLQGDVRWR KLFSFTKYFL KIEKNGKVSG TKKENCPYSI LEITSVEIGV VAVKAINSNY YLAMNKKGKL YGSKEFNNDC KLKERIEENG YNTYASFNWQ HNGRQMYVAL NGKGAPRRGQ KTRRKNTSAH FLPMVVHS
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