Regulator of G-protein signaling 5 (RGS5)

About Regulator of G-protein signaling 5

Regulator of G-protein signaling 5 (RGS5) is a protein from Homo sapiens identified by UniProt accession O15539, 181 residues long. MolForge cross-references it against 0 known binders and 265 disease associations.

Target properties

Protein name	Regulator of G-protein signaling 5
UniProt accession	O15539
Gene	RGS5
Organism	Homo sapiens
Length	181 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O15539-F1	alphafold	PREDICTED	85.58	—

Amino-acid sequence (181 residues)

MCKGLAALPH SCLERAKEIK IKLGILLQKP DSVGDLVIPY NEKPEKPAKT QKTSLDEALQ WRDSLDKLLQ NNYGLASFKS FLKSEFSEEN LEFWIACEDY KKIKSPAKMA EKAKQIYEEF IQTEAPKEVN IDHFTKDITM KNLVEPSLSS FDMAQKRIHA LMEKDSLPRF VRSEFYQELI K

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards