Fatty acid-binding protein, brain (FABP7)

About Fatty acid-binding protein, brain

Fatty acid-binding protein, brain (FABP7) is a protein from Homo sapiens identified by UniProt accession O15540, 132 residues long. MolForge cross-references it against 0 known binders and 186 disease associations.

Target properties

Protein name	Fatty acid-binding protein, brain
UniProt accession	O15540
Gene	FABP7
Organism	Homo sapiens
Length	132 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (186)

Diseases linked to this target (Open Targets).

protein measurement · score 0.22
drug use measurement · score 0.11
neoplasm · score 0.11
breast cancer · score 0.10
glioblastoma multiforme · score 0.10
renal cell carcinoma · score 0.10
melanoma · score 0.09
Blackfan-Diamond anemia · score 0.09
glioma · score 0.08
non-small cell lung carcinoma · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O15540-F1	alphafold	PREDICTED	96.30	—

Amino-acid sequence (132 residues)

MVEAFCATWK LTNSQNFDEY MKALGVGFAT RQVGNVTKPT VIISQEGDKV VIRTLSTFKN TEISFQLGEE FDETTADDRN CKSVVSLDGD KLVHIQKWDG KETNFVREIK DGKMVMTLTF GDVVAVRHYE KA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards