About Zinc finger and BTB domain-containing protein 24
Zinc finger and BTB domain-containing protein 24 (ZBTB24) is a protein
from Homo sapiens identified by UniProt accession
O43167, 697 residues long.
MolForge cross-references it against 0 known binders and
108 disease associations.
Target properties
| Protein name | Zinc finger and BTB domain-containing protein 24 |
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| UniProt accession | O43167 |
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| Gene | ZBTB24 |
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| Organism | Homo sapiens |
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| Length | 697 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (108)
Diseases linked to this target (Open Targets).
- ICF syndrome · score 0.77
- Intellectual disability · score 0.37
- genetic disorder · score 0.19
- body height · score 0.18
- hemoglobin measurement · score 0.14
- Kabuki syndrome · score 0.12
- red blood cell density measurement · score 0.10
- sitting height measurement · score 0.10
- reticulocyte count · score 0.10
- granulocyte percentage of myeloid white cells · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O43167-F1 | alphafold | PREDICTED | 56.61 | — |
Amino-acid sequence (697 residues)
MAETSPEPSG QLVVHSDAHS DTVLASFEDQ RKKGFLCDIT LIVENVHFRA HKALLAASSE YFSMMFAEEG EIGQSIYMLE GMVADTFGIL LEFIYTGYLH ASEKSTEQIL ATAQFLKVYD LVKAYTDFQN NHSSPKPTTL NTAGAPVVVI SNKKNDPPKR KRGRPKKVNT LQEEKSELAA EEEIQLRVNN SVQNRQNFVV KGDSGVLNEQ IAAKEKEESE PTCEPSREEE MPVEKDENYD PKTEDGQASQ SRYSKRRIWR SVKLKDYKLV GDQEDHGSAK RICGRRKRPG GPEARCKDCG KVFKYNHFLA IHQRSHTGER PFKCNECGKG FAQKHSLQVH TRMHTGERPY TCTVCSKALT TKHSLLEHMS LHSGQKSFTC DQCGKYFSQN RQLKSHYRVH TGHSLPECKD CHRKFMDVSQ LKKHLRTHTG EKPFTCEICG KSFTAKSSLQ THIRIHRGEK PYSCGICGKS FSDSSAKRRH CILHTGKKPF SCPECNLQFA RLDNLKAHLK IHSKEKHASD ASSISGSSNT EEVRNILQLQ PYQLSTSGEQ EIQLLVTDSV HNINFMPGPS QGISIVTAES SQNMTADQAA NLTLLTQQPE QLQNLILSAQ QEQTEHIQSL NMIESQMGPS QTEPVHVITL SKETLEHLHA HQEQTEELHL ATSTSDPAQH LQLTQEPGPP PPTHHVPQPT PLGQEQS
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