Cytochrome b5 type B (CYB5B)

About Cytochrome b5 type B

Cytochrome b5 type B (CYB5B) is a protein from Homo sapiens identified by UniProt accession O43169, 150 residues long. MolForge cross-references it against 0 known binders and 48 disease associations.

Target properties

Protein name	Cytochrome b5 type B
UniProt accession	O43169
Gene	CYB5B
Organism	Homo sapiens
Length	150 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (48)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.42
Parkinson disease · score 0.30
Alzheimer disease · score 0.30
multiple sclerosis · score 0.30
lysosomal storage disease · score 0.30
pack-years measurement · score 0.24
systolic blood pressure · score 0.24
thyroid disease · score 0.19
heel bone mineral density · score 0.18
body fat percentage · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O43169-F1	alphafold	PREDICTED	80.79	—

Amino-acid sequence (150 residues)

MSGSMATAEA SGSDGKGQEV ETSVTYYRLE EVAKRNSLKE LWLVIHGRVY DVTRFLNEHP GGEEVLLEQA GVDASESFED VGHSSDAREM LKQYYIGDIH PSDLKPESGS KDPSKNDTCK SCWAYWILPI IGAVLLGFLY RYYTSESKSS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards