About Kallikrein-10
Kallikrein-10 (KLK10) is a protein
from Homo sapiens identified by UniProt accession
O43240, 276 residues long.
MolForge cross-references it against 0 known binders and
114 disease associations.
Target properties
| Protein name | Kallikrein-10 |
|---|
| UniProt accession | O43240 |
|---|
| Gene | KLK10 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 276 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (114)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.37
- vitamin D measurement · score 0.37
- protein measurement · score 0.24
- neoplasm · score 0.09
- acute lymphoblastic leukemia · score 0.08
- chronic obstructive pulmonary disease · score 0.07
- kallikrein-11 measurement · score 0.06
- in situ carcinoma · score 0.06
- gonorrhea · score 0.05
- atherosclerosis · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O43240-F1 | alphafold | PREDICTED | 80.18 | — |
Amino-acid sequence (276 residues)
MRAPHLHLSA ASGARALAKL LPLLMAQLWA AEAALLPQND TRLDPEAYGS PCARGSQPWQ VSLFNGLSFH CAGVLVDQSW VLTAAHCGNK PLWARVGDDH LLLLQGEQLR RTTRSVVHPK YHQGSGPILP RRTDEHDLML LKLARPVVLG PRVRALQLPY RCAQPGDQCQ VAGWGTTAAR RVKYNKGLTC SSITILSPKE CEVFYPGVVT NNMICAGLDR GQDPCQSDSG GPLVCDETLQ GILSWGVYPC GSAQHPAVYT QICKYMSWIN KVIRSN
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