About Ciliary microtubule inner protein 4
Ciliary microtubule inner protein 4 (CIMIP4) is a protein
from Homo sapiens identified by UniProt accession
O43247, 280 residues long.
MolForge cross-references it against 0 known binders and
9 disease associations.
Target properties
| Protein name | Ciliary microtubule inner protein 4 |
|---|
| UniProt accession | O43247 |
|---|
| Gene | CIMIP4 |
|---|
| Organism | Homo sapiens |
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| Length | 280 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (9)
Diseases linked to this target (Open Targets).
- protein measurement · score 0.22
- eye colour measurement · score 0.17
- mean corpuscular hemoglobin · score 0.05
- calf circumference measurement · score 0.01
- chronic myelogenous leukemia · score 0.01
- Abnormal sperm morphology · score 0.01
- breast cancer · score 0.00
- cancer · score 0.00
- Azoospermia · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O43247-F1 | alphafold | PREDICTED | 59.80 | — |
Amino-acid sequence (280 residues)
MELGHGAGTT TFTRAHLNDK EGQQDLDPWK AAYSSLDTSK FKNQGLSSPQ PLPLGASAQG SSLGQCHLKE IPPPPPTAAS RDSLGMDPQS RSLKNAGSRS SSRENRATSG EGAQPCQGTD DGPSLGAQDQ RSTPTNQKGS IIPNNIRHKF GSNVVDQLVS EEQAQKAIDE VFEGQKRASS WPSRTQNPVE ISSVFSDYYD LGYNMRSNLF RGAAEETKSL MKASYTPEVI EKSVRDLEHW HGRKTDDLGR WHQKNAMNLN LQKALEEKYG ENSKSKSSKY
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