About Homeobox protein Hox-C11
Homeobox protein Hox-C11 (HOXC11) is a protein
from Homo sapiens identified by UniProt accession
O43248, 304 residues long.
MolForge cross-references it against 0 known binders and
156 disease associations.
Target properties
| Protein name | Homeobox protein Hox-C11 |
|---|
| UniProt accession | O43248 |
|---|
| Gene | HOXC11 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 304 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (156)
Diseases linked to this target (Open Targets).
- gliomatosis cerebri · score 0.37
- colorectal adenocarcinoma · score 0.37
- bile duct carcinoma · score 0.37
- lung adenocarcinoma · score 0.30
- non-small cell lung carcinoma · score 0.29
- colon adenocarcinoma · score 0.29
- melanoma · score 0.29
- esophageal adenocarcinoma · score 0.29
- gastric adenocarcinoma · score 0.28
- gastric carcinoma · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O43248-F1 | alphafold | PREDICTED | 59.39 | — |
Amino-acid sequence (304 residues)
MFNSVNLGNF CSPSRKERGA DFGERGSCAS NLYLPSCTYY MPEFSTVSSF LPQAPSRQIS YPYSAQVPPV REVSYGLEPS GKWHHRNSYS SCYAAADELM HRECLPPSTV TEILMKNEGS YGGHHHPSAP HATPAGFYSS VNKNSVLPQA FDRFFDNAYC GGGDPPAEPP CSGKGEAKGE PEAPPASGLA SRAEAGAEAE AEEENTNPSS SGSAHSVAKE PAKGAAPNAP RTRKKRCPYS KFQIRELERE FFFNVYINKE KRLQLSRMLN LTDRQVKIWF QNRRMKEKKL SRDRLQYFSG NPLL
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