RNA binding protein fox-1 homolog 2 (RBFOX2)

About RNA binding protein fox-1 homolog 2

RNA binding protein fox-1 homolog 2 (RBFOX2) is a protein from Homo sapiens identified by UniProt accession O43251, 390 residues long. MolForge cross-references it against 0 known binders and 115 disease associations.

Target properties

Protein name	RNA binding protein fox-1 homolog 2
UniProt accession	O43251
Gene	RBFOX2
Organism	Homo sapiens
Length	390 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O43251-F1	alphafold	PREDICTED	54.89	—

Amino-acid sequence (390 residues)

MQNEPLTPGY HGFPARDSQG NQEPTTTPDA MVQPFTTIPF PPPPQNGIPT EYGVPHTQDY AGQTGEHNLT LYGSTQAHGE QSSNSPSTQN GSLTTEGGAQ TDGQQSQTQS SENSESKSTP KRLHVSNIPF RFRDPDLRQM FGQFGKILDV EIIFNERGSK GFGFVTFENS ADADRAREKL HGTVVEGRKI EVNNATARVM TNKKMVTPYA NGWKLSPVVG AVYGPELYAA SSFQADVSLG NDAAVPLSGR GGINTYIPLI SLPLVPGFPY PTAATTAAAF RGAHLRGRGR TVYGAVRAVP PTAIPAYPGV VYQDGFYGAD LYGGYAAYRY AQPATATAAT AAAAAAAAYS DGYGRVYTAD PYHALAPAAS YGVGAVASLY RGGYSRFAPY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards