About Zinc finger protein 264
Zinc finger protein 264 (ZNF264) is a protein
from Homo sapiens identified by UniProt accession
O43296, 627 residues long.
MolForge cross-references it against 0 known binders and
20 disease associations.
Target properties
| Protein name | Zinc finger protein 264 |
|---|
| UniProt accession | O43296 |
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| Gene | ZNF264 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 627 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (20)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.24
- body mass index · score 0.21
- mean platelet volume · score 0.10
- anxiety · score 0.06
- high density lipoprotein cholesterol measurement · score 0.03
- triglyceride measurement · score 0.03
- gut microbiome measurement · score 0.02
- acute myeloid leukemia · score 0.01
- myeloid sarcoma · score 0.01
- Pick disease · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O43296-F1 | alphafold | PREDICTED | 65.71 | — |
Amino-acid sequence (627 residues)
MAAAVLTDRA QVSVTFDDVA VTFTKEEWGQ LDLAQRTLYQ EVMLENCGLL VSLGCPVPKA ELICHLEHGQ EPWTRKEDLS QDTCPGDKGK PKTTEPTTCE PALSEGISLQ GQVTQGNSVD SQLGQAEDQD GLSEMQEGHF RPGIDPQEKS PGKMSPECDG LGTADGVCSR IGQEQVSPGD RVRSHNSCES GKDPMIQEEE NNFKCSECGK VFNKKHLLAG HEKIHSGVKP YECTECGKTF IKSTHLLQHH MIHTGERPYE CMECGKAFNR KSYLTQHQRI HSGEKPYKCN ECGKAFTHRS NFVLHNRRHT GEKSFVCTEC GQVFRHRPGF LRHYVVHSGE NPYECLECGK VFKHRSYLMW HQQTHTGEKP YECSECGKVF LESAALIHHY VIHTGEKPFE CLECGKAFNH RSYLKRHQRI HTGEKPFVCS ECGKAFTHCS TFILHKRAHT GEKPFECKEC GKAFSNRKDL IRHFSIHTGE KPYECVECGK AFTRMSGLTR HKRIHSGEKP YECVECGKSF CWSTNLIRHA IIHTGEKPYK CSECGKAFSR SSSLTQHQRM HTGKNPISVT DVGRPFTSGQ TSVTLRELLL GKDFLNVTTE ANILPEETSS SASDQPYQRE TPQVSSL
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