About Protein MTSS 1
Protein MTSS 1 (MTSS1) is a protein
from Homo sapiens identified by UniProt accession
O43312, 755 residues long.
MolForge cross-references it against 0 known binders and
308 disease associations.
Target properties
| Protein name | Protein MTSS 1 |
|---|
| UniProt accession | O43312 |
|---|
| Gene | MTSS1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 755 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (308)
Diseases linked to this target (Open Targets).
- electrocardiography · score 0.36
- hematocrit · score 0.36
- platelet count · score 0.35
- left ventricular structural measurement · score 0.35
- hemoglobin measurement · score 0.33
- PR interval · score 0.32
- left ventricular ejection fraction measurement · score 0.32
- left ventricular systolic function measurement · score 0.32
- atrial fibrillation · score 0.32
- platelet crit · score 0.31
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O43312-F1 | alphafold | PREDICTED | 61.55 | — |
Amino-acid sequence (755 residues)
MEAVIEKECS ALGGLFQTII SDMKGSYPVW EDFINKAGKL QSQLRTTVVA AAAFLDAFQK VADMATNTRG GTREIGSALT RMCMRHRSIE AKLRQFSSAL IDCLINPLQE QMEEWKKVAN QLDKDHAKEY KKARQEIKKK SSDTLKLQKK AKKGRGDIQP QLDSALQDVN DKYLLLEETE KQAVRKALIE ERGRFCTFIS MLRPVIEEEI SMLGEITHLQ TISEDLKSLT MDPHKLPSSS EQVILDLKGS DYSWSYQTPP SSPSTTMSRK SSVCSSLNSV NSSDSRSSGS HSHSPSSHYR YRSSNLAQQA PVRLSSVSSH DSGFISQDAF QSKSPSPMPP EAPNQLSNGF SHYSLSSESH VGPTGAGLFP HCLPASRLLP RVTSVHLPDY AHYYTIGPGM FPSSQIPSWK DWAKPGPYDQ PLVNTLQRRK EKREPDPNGG GPTTASGPPA AAEEAQRPRS MTVSAATRPG EEMEACEELA LALSRGLQLD TQRSSRDSLQ CSSGYSTQTT TPCCSEDTIP SQVSDYDYFS VSGDQEADQQ EFDKSSTIPR NSDISQSYRR MFQAKRPAST AGLPTTLGPA MVTPGVATIR RTPSTKPSVR RGTIGAGPIP IKTPVIPVKT PTVPDLPGVL PAPPDGPEER GEHSPESPSV GEGPQGVTSM PSSMWSGQAS VNPPLPGPKP SIPEEHRQAI PESEAEDQER EPPSATVSPG QIPESDPADL SPRDTPQGED MLNAIRRGVK LKKTTTNDRS APRFS
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