About Fibroblast growth factor 16
Fibroblast growth factor 16 (FGF16) is a protein
from Homo sapiens identified by UniProt accession
O43320, 207 residues long.
MolForge cross-references it against 0 known binders and
68 disease associations.
Target properties
| Protein name | Fibroblast growth factor 16 |
|---|
| UniProt accession | O43320 |
|---|
| Gene | FGF16 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 207 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (68)
Diseases linked to this target (Open Targets).
- syndactyly type 8 · score 0.68
- cancer · score 0.59
- bone development disease · score 0.59
- acrocephalosyndactyly · score 0.37
- craniosynostosis · score 0.37
- ovarian carcinoma · score 0.37
- female reproductive endometrioid cancer · score 0.37
- cutaneous melanoma · score 0.29
- hepatocellular carcinoma · score 0.08
- Graves disease · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O43320-F1 | alphafold | PREDICTED | 81.61 | — |
Amino-acid sequence (207 residues)
MAEVGGVFAS LDWDLHGFSS SLGNVPLADS PGFLNERLGQ IEGKLQRGSP TDFAHLKGIL RRRQLYCRTG FHLEIFPNGT VHGTRHDHSR FGILEFISLA VGLISIRGVD SGLYLGMNER GELYGSKKLT RECVFREQFE ENWYNTYAST LYKHSDSERQ YYVALNKDGS PREGYRTKRH QKFTHFLPRP VDPSKLPSMS RDLFHYR
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