Eukaryotic translation elongation factor 1…

About Eukaryotic translation elongation factor 1 epsilon-1

Eukaryotic translation elongation factor 1 epsilon-1 (EEF1E1) is a protein from Homo sapiens identified by UniProt accession O43324, 174 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.

Target properties

Protein name	Eukaryotic translation elongation factor 1 epsilon-1
UniProt accession	O43324
Gene	EEF1E1
Organism	Homo sapiens
Length	174 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (41)

Diseases linked to this target (Open Targets).

FEV/FVC ratio · score 0.29
neoplasm · score 0.08
hepatocellular carcinoma · score 0.08
non-small cell lung carcinoma · score 0.07
lung cancer · score 0.05
cancer · score 0.05
mean corpuscular volume · score 0.03
mean corpuscular hemoglobin concentration · score 0.03
mean corpuscular hemoglobin · score 0.02
colorectal cancer · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O43324-F1	alphafold	PREDICTED	92.37	—

Amino-acid sequence (174 residues)

MAAAAELSLL EKSLGLSKGN KYSAQGERQI PVLQTNNGPS LTGLTTIAAH LVKQANKEYL LGSTAEEKAI VQQWLEYRVT QVDGHSSKND IHTLLKDLNS YLEDKVYLTG YNFTLADILL YYGLHRFIVD LTVQEKEKYL NVSRWFCHIQ HYPGIRQHLS SVVFIKNRLY TNSH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Eukaryotic translation elongation factor 1 epsilon-1 (EEF1E1)