About Zinc finger protein 749
Zinc finger protein 749 (ZNF749) is a protein
from Homo sapiens identified by UniProt accession
O43361, 778 residues long.
MolForge cross-references it against 0 known binders and
3 disease associations.
Target properties
| Protein name | Zinc finger protein 749 |
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| UniProt accession | O43361 |
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| Gene | ZNF749 |
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| Organism | Homo sapiens |
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| Length | 778 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (3)
Diseases linked to this target (Open Targets).
- appendicular lean mass · score 0.02
- Rheumatoid arthritis · score 0.00
- Infertility · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O43361-F1 | alphafold | PREDICTED | 59.47 | — |
Amino-acid sequence (778 residues)
MNLTEDCMVF EDVAIYFSQE EWGILNDAQR HLHSNVMLEN FALLSSVGCW HGAKDEEVPS KQCVSVRVLQ VTIPKPALST LKAQPCKMCS SILKDILHLA EHDGTHPEQG LYTCAAEHDL HQKEQIREKL TRSDEWRPSF VNHSAHVGER NFTCTQGGKD FTASSDLLQQ QVLNSGWKLY RDTQDGEAFQ GEQNDFNSSQ GGKDFCHQHG LFEHQKTHNG ERPYEFSECG ELFRYNSNLI KYQQNHAGER PYEGTEYGKT FIRKSNLVQH QKIHSEGFLS KRSDPIEHQE ILSRPTPYEC TQCGKAFLTQ AHLVGHQKTH TGEQPYECNK CGKFFMYNSK LIRHQKVHTG ERRYECSECG KLFMDSFTLG RHQRVHTGER PFECSICGKF FSHRSTLNMH QRVHAGKRLY KCSECGKAFS LKHNVVQHLK IHTGERPYEC TECEKAFVRK SHLVQHQKIH TDAFSKRSDL IQHKRIDIRP RPYTCSECGK AFLTQAHLVG HQKIHTGERP YECTQCAKAF VRKSHLVQHE KIHTDAFSKR SDLIQHKRID LRPRPYVCSE CGKAFLTQAH LDGHQKIQTG ERRYECNECG KFFLDSYKLV IHQRIHTGEK PYKCSKCGKF FRYRCTLSRH QKVHTGERPY ECSECGKFFR DSYKLIIHQR VHTGEKPYEC SNCGKFLRYR STFIKHHKVC TGEKPHECSK CRELFRTKSS LIIHQQSHTG ESPFKLRECG KDFNKCNTGQ RQKTHTGERS YECGESSKVF KYNSSLIKHQ IIHTGKRP
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